Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | XPO1 | O14980 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900032 | 0.84 | KYAT1 (0.46) | MAPTGAAKYAT1GPR35TRPV1 | |
| SCHEMBL271270 | 0.83 | HPGD (0.41) | NPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL3315040 | 0.83 | MEN1 (0.49) | MAPTGAANPC1ALDH1A1MEN1 | |
| SCHEMBL9585644 | 0.81 | MAPT (0.43) | MAPTGAAKYAT1GPR35TRPV1 | |
| SCHEMBL9052329 | 0.78 | MMP8 (0.50) | MAPTGAATRPV1NPC1ALDH1A1 | |
| SCHEMBL23461767 | 0.77 | GAA (0.45) | MAPTGAAKYAT1TRPV1XPO1 | |
| SCHEMBL15918132 | 0.77 | CASP1 (0.59) | MAPTGAAKYAT1GPR35TRPV1 | |
| SCHEMBL29888742 | 0.77 | GAA (0.45) | MAPTGAAKYAT1TRPV1XPO1 | |
| SCHEMBL16322386 | 0.77 | PSEN1 (0.49) | MAPTGAATRPV1NPC1ALDH1A1 | |
| SCHEMBL28825411 | 0.77 | MAPT (0.44) | MAPTGAATRPV1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |