Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750606 | 0.80 | P2RY1 (0.51) | MAPTALDH1A1HPGDTSHRP2RY1 | |
| SCHEMBL5546372 | 0.79 | CCNA2 (0.45) | MAPTCRHR1ALDH1A1HPGDTSHR | |
| SCHEMBL1928591 | 0.78 | MAPT (0.36) | MAPTCRHR1ALDH1A1HPGDTSHR | |
| SCHEMBL8554826 | 0.78 | ALDH1A1 (0.50) | MAPTALDH1A1HPGDTSHRPOLB | |
| SCHEMBL3748422 | 0.78 | LCK (0.48) | PI4KB | |
| Hydrochloric Acid SCHEMBL8554359 | 0.77 | ALDH1A1 (0.49) | MAPTALDH1A1HPGDTSHRPOLB | |
| SCHEMBL9750613 | 0.76 | RAB9A (0.55) | MAPTHPGDTSHRP2RY1NPC1 | |
| SCHEMBL1539932 | 0.76 | P2RY1 (0.33) | MAPTCRHR1ALDH1A1P2RY1POLB | |
| SCHEMBL28144507 | 0.75 | ALDH1A1 (0.49) | MAPTCRHR1ALDH1A1HPGDPOLB | |
| SCHEMBL5528567 | 0.75 | MAPT (0.40) | MAPTALDH1A1HPGDTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | claimed |