Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750642 | 0.79 | MAPT (0.38) | MAPTNPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28144507 | 0.77 | ALDH1A1 (0.49) | MAPTMEN1KMT2ACRHR1ALDH1A1 | |
| SCHEMBL1928591 | 0.77 | MAPT (0.36) | MAPTNPC1MEN1KMT2ACRHR1 | |
| SCHEMBL8556409 | 0.77 | NPC1 (0.60) | CCNA2CDK2MAPTNPC1CDK5 | |
| SCHEMBL9643966 | 0.76 | MAPT (0.38) | MAPTMEN1KMT2ASMN1; SMN2CRHR1 | |
| SCHEMBL8552123 | 0.76 | CCNA2 (0.48) | CCNA2CDK2MAPTNPC1CDK5 | |
| SCHEMBL5559263 | 0.76 | MAPT (0.39) | MAPTNPC1MEN1MAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL8556705 | 0.76 | NPC1 (0.58) | CCNA2CDK2MAPTNPC1CDK5 | |
| SCHEMBL3748422 | 0.74 | LCK (0.48) | — | |
| SCHEMBL975710 | 0.73 | MAPT (0.60) | MAPTNPC1MEN1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000649-A9 | SUBSTITUTED QUINAZOLINE DERIVATIVES AND THEIR USE AS INHIBITORS | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | WO | disclosed |
| EP-0639574-B1 | 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms | LUCKY LTD (KR) | 1998-06-10 | — | — | EP | disclosed |
| US-5514643-A | FUNGICIDES FOR PLANTS | LUCKY LTD. (KR) | 1996-05-07 | — | — | US | disclosed |
| EP-0639574-A1 | 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms | LUCKY LTD. (KR) | 1995-02-22 | — | — | EP | disclosed |