⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23928729 | 0.80 | — | — | |
| SCHEMBL394606 | 0.78 | DNM1 (0.40) | — | |
| SCHEMBL10050128 | 0.78 | — | — | |
| SCHEMBL11126725 | 0.78 | — | — | |
| SCHEMBL5666084 | 0.75 | — | — | |
| SCHEMBL17514073 | 0.73 | — | — | |
| SCHEMBL13132156 | 0.73 | — | — | |
| SCHEMBL91093 | 0.73 | — | — | |
| SCHEMBL16588372 | 0.73 | — | — | |
| SCHEMBL8994095 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321548-A4 | NOVEL AMPHIPHILIC NUCLEIC ACID CONJUGATES | — | 1991-01-30 | — | — | EP | disclosed |
| US-4904582-A | Novel amphiphilic nucleic acid conjugates | SYNTHETIC GENETICS (US) | 1990-02-27 | — | — | US | disclosed |
| WO-1989005853-A1 | NUCLEIC ACID CHELATE CONJUGATE AS THERAPEUTIC AND DIAGNOSTIC AGENTS | SYNTHETIC GENETICS (US) | 1989-06-29 | — | — | WO | disclosed |
| EP-0321548-A1 | NOVEL AMPHIPHILIC NUCLEIC ACID CONJUGATES | SYNTHETIC GENETICS (US) | 1989-06-28 | — | — | EP | disclosed |
| WO-1988009810-A1 | NOVEL AMPHIPHILIC NUCLEIC ACID CONJUGATES | SYNTHETIC GENETICS (US) | 1988-12-15 | — | — | WO | disclosed |