Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27812647 | 0.85 | GPR35 (0.50) | GPR35TDP1TSHRSMN1; SMN2CTSB | |
| SCHEMBL258792 | 0.84 | GPR35 (0.55) | GPR35TDP1TSHRSMN1; SMN2CTSB | |
| SCHEMBL1896801 | 0.83 | TDP1 (0.56) | GPR35TDP1TSHRSMN1; SMN2CTSB | |
| SCHEMBL7520585 | 0.83 | TDP1 (0.60) | GPR35TDP1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL11510078 | 0.82 | GPR35 (0.53) | GPR35TDP1TSHRSMN1; SMN2CTSB | |
| Ammonia Solution, Strong SCHEMBL28335602 | 0.82 | GPR35 (0.53) | GPR35TDP1TSHRSMN1; SMN2CTSB | |
| SCHEMBL2651124 | 0.82 | TDP1 (0.54) | GPR35TDP1TSHRSMN1; SMN2CTSB | |
| SCHEMBL6858240 | 0.82 | MCL1 (0.49) | GPR35TDP1TSHRSMN1; SMN2TP53 | |
| SCHEMBL145978 | 0.81 | GPR35 (0.67) | GPR35TDP1TSHRSMN1; SMN2CTSB | |
| SCHEMBL28755195 | 0.80 | TDP1 (0.52) | GPR35TDP1TSHRSMN1; SMN2CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028355-A | Conductive polyurethane foam containing picric acid and analog thereof | CREST-FOAM CORPORATION (US) | 1991-07-02 | — | — | US | claimed |
| EP-0316446-A4 | IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD | — | 1991-03-20 | — | — | EP | claimed |
| US-4982034-A | ALKYLATION, OXIDATIVE DEHYDROGENATION, DISTILLATION, EVAPORATION, ADSORPTION | AMOCO CORPORATION (US) | 1991-01-01 | — | — | US | claimed |
| EP-0316446-A1 | IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD | CREST-FOAM Corp. (US) | 1989-05-24 | — | — | EP | claimed |
| WO-1988009350-A1 | IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD | CREST-FOAM COPORATION (US) | 1988-12-01 | — | — | WO | claimed |
| US-10138183-B2 | Process and composition for inhibiting the polymerization of cyclopentadiene compounds | EVONIK DEGUSSA GMBH (DE) | 2018-11-27 | — | — | US | disclosed |
| US-9670116-B2 | Process and composition for inhibiting the polymerization of cyclopentadiene compounds | EVONIK DEGUSSA GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| US-9493382-B2 | Process and composition for inhibiting the polymerization of cyclopentadiene compounds | EVONIK DEGUSSA GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| US-20160237008-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20160237346-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20140288337-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | EVONIK INDUSTRIES AG (DE) | 2014-09-25 | — | — | US | disclosed |
| CN-100338020-C | Tech. of preparing 2,4-dinitro methyl-phenoxide by nitro methyl-phenoxide interrupter nitration | JIASEN CHEMICAL INDUSTRY CO LT (CN) | 2007-09-19 | — | — | CN | disclosed |
| CN-1861571-A | Tech. of preparing 2,4-diamino methy-phenoxide using 2,4-dinictro methyl phenoxide | JIASEN CHEMICAL INDUSTRY CO LT (CN) | 2006-11-15 | — | — | CN | disclosed |
| CN-1861565-A | Tech. of preparing 2,4-dinitro methyl-phenoxide by nitro methyl-phenoxide interrupter nitration | JIASEN CHEMICAL INDUSTRY CO LT (CN) | 2006-11-15 | — | — | CN | disclosed |
| US-5028355-A | Conductive polyurethane foam containing picric acid and analog thereof | CREST-FOAM CORPORATION (US) | 1991-07-02 | — | — | US | disclosed |
| EP-0316446-A4 | IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD | — | 1991-03-20 | — | — | EP | disclosed |
| US-4982034-A | ALKYLATION, OXIDATIVE DEHYDROGENATION, DISTILLATION, EVAPORATION, ADSORPTION | AMOCO CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| US-4886626-A | REDUCTION OF ELECTRICAL RESISTANCE | CREST-FOAM CORPORATION (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0316446-A1 | IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD | CREST-FOAM Corp. (US) | 1989-05-24 | — | — | EP | disclosed |
| WO-1988009350-A1 | IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD | CREST-FOAM COPORATION (US) | 1988-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288337-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | CYC1, SQOR, UQCRB | GPR35 4823/4885TDP1 2359/4885TSHR 4883/4885 |
| US-20160237008-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | CYC1, SQOR, UQCRB | GPR35 4823/4885TDP1 2359/4885TSHR 4883/4885 |
| US-10138183-B2 | Process and composition for inhibiting the polymerization of cyclopentadiene compounds | CYC1, SQOR, UQCRB | GPR35 4823/4885TDP1 2359/4885TSHR 4883/4885 |
| US-20160237346-A1 | PROCESS AND COMPOSITION FOR INHIBITING THE POLYMERIZATION OF CYCLOPENTADIENE COMPOUNDS | CYC1, SQOR, UQCRB | GPR35 4823/4885TDP1 2359/4885TSHR 4883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.