SCHEMBL9750940

SCHEMBL9750940

COC(=O)CC(O)CC(O)CCc1c(-c2ccc(F)cc2)c(C)n(-c2ccccc2)c1C

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 11/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9750867 0.91 HMGCR (0.66) HMGCR
SCHEMBL9751001 0.87 HMGCR (1.00) HMGCR
SCHEMBL9750889 0.80 HMGCR (0.78) HMGCR
SCHEMBL9751023 0.79 HMGCR (0.83) HMGCR
SCHEMBL9750901 0.77 HMGCR (0.53) HMGCR
SCHEMBL9756768 0.77 HMGCR (0.53) HMGCR
SCHEMBL9519597 0.75 HMGCR (0.65) HMGCR
SCHEMBL9750928 0.75 HMGCR (0.55) HMGCR
SCHEMBL9750906 0.74 HMGCR (0.78) HMGCR
SCHEMBL31061598 0.74 HMGCR (0.60) HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5055484-A Anticholesterol and antilipemic agent HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-08 US disclosed