Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750809 | 0.88 | HMGCR (0.68) | HMGCR | |
| SCHEMBL9518621 | 0.85 | HMGCR (0.62) | HMGCR | |
| SCHEMBL9750835 | 0.81 | HMGCR (0.79) | HMGCR | |
| SCHEMBL9750867 | 0.81 | HMGCR (0.66) | HMGCR | |
| SCHEMBL9518306 | 0.80 | HMGCR (0.81) | HMGCR | |
| SCHEMBL9756768 | 0.80 | HMGCR (0.53) | HMGCR | |
| SCHEMBL9750906 | 0.78 | HMGCR (0.78) | HMGCR | |
| SCHEMBL9750940 | 0.77 | HMGCR (0.79) | HMGCR | |
| SCHEMBL9518442 | 0.75 | HMGCR (0.51) | HMGCR | |
| SCHEMBL9518809 | 0.74 | HMGCR (0.43) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |