Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 9/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | RHOC | P08134 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750940 | 0.91 | HMGCR (0.79) | HMGCR | |
| SCHEMBL9751023 | 0.88 | HMGCR (0.83) | HMGCR | |
| SCHEMBL9750928 | 0.85 | HMGCR (0.55) | HMGCRNR1I2ABCB11RHOCCYP3A4 | |
| SCHEMBL31061598 | 0.83 | HMGCR (0.60) | HMGCRNR1I2ABCB11RHOCCYP3A4 | |
| SCHEMBL9756768 | 0.83 | HMGCR (0.53) | HMGCRNR1I2ABCB11RHOCCYP3A4 | |
| SCHEMBL9519597 | 0.81 | HMGCR (0.65) | HMGCR | |
| SCHEMBL9750901 | 0.81 | HMGCR (0.53) | HMGCR | |
| SCHEMBL9751001 | 0.79 | HMGCR (1.00) | HMGCR | |
| SCHEMBL9750889 | 0.75 | HMGCR (0.78) | HMGCRABCB11 | |
| SCHEMBL9518614 | 0.75 | HMGCR (0.48) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |