Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751007 | 0.81 | HMGCR (0.56) | HMGCRABCB1PDE11AMEN1KMT2A | |
| SCHEMBL9751002 | 0.81 | HMGCR (0.56) | HMGCRABCB1PDE11AMEN1KMT2A | |
| SCHEMBL9750954 | 0.80 | HMGCR (0.57) | HMGCRABCB1PDE11AMEN1KMT2A | |
| SCHEMBL9750986 | 0.72 | ABCB1 (0.52) | HMGCRABCB1PDE11AMEN1KMT2A | |
| SCHEMBL9750959 | 0.70 | ABCB1 (0.49) | HMGCRABCB1PDE11AMEN1KMT2A | |
| SCHEMBL9750927 | 0.69 | HMGCR (0.66) | HMGCRABCB1 | |
| SCHEMBL10506117 | 0.69 | ABCB1 (0.65) | HMGCRABCB1MEN1KMT2AMAPT | |
| SCHEMBL9518155 | 0.69 | HMGCR (0.53) | HMGCRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9750857 | 0.69 | HMGCR (0.78) | HMGCR | |
| SCHEMBL7834905 | 0.67 | CA12 (0.52) | MAPTSQORKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |