Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | HMGCR | P04035 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10506117 | 0.80 | ABCB1 (0.65) | ABCB1HMGCRMEN1KMT2AALDH1A1 | |
| SCHEMBL9751015 | 0.76 | MEN1 (0.61) | ABCB1HMGCRMEN1KMT2AALDH1A1 | |
| SCHEMBL9750959 | 0.73 | ABCB1 (0.49) | ABCB1HMGCRMEN1KMT2AALDH1A1 | |
| SCHEMBL9750981 | 0.72 | HMGCR (0.53) | ABCB1HMGCRMEN1KMT2AALDH1A1 | |
| SCHEMBL9750954 | 0.69 | HMGCR (0.57) | ABCB1HMGCRMEN1KMT2AALDH1A1 | |
| SCHEMBL2880014 | 0.69 | ALDH1A1 (0.61) | ABCB1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL22033235 | 0.69 | ABCB1 (1.00) | ABCB1HMGCRMEN1KMT2AALDH1A1 | |
| SCHEMBL9750874 | 0.68 | HMGCR (0.41) | ABCB1HMGCRALDH1A1KDM4EGAA | |
| SCHEMBL9750852 | 0.68 | HMGCR (0.53) | ABCB1HMGCRMEN1KMT2AALDH1A1 | |
| SCHEMBL7834905 | 0.67 | CA12 (0.52) | ALDH1A1HPGDKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |