Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751103 | 0.95 | L3MBTL1 (0.47) | L3MBTL1 | |
| SCHEMBL9751036 | 0.86 | SMN1; SMN2 (0.48) | L3MBTL1ACHE | |
| SCHEMBL3974252 | 0.74 | MEN1 (0.50) | L3MBTL1HRH3 | |
| SCHEMBL2964590 | 0.73 | MAOB (0.50) | L3MBTL1HRH3 | |
| SCHEMBL3975479 | 0.73 | MAOB (0.50) | L3MBTL1HRH3 | |
| SCHEMBL596252 | 0.71 | L3MBTL1 (0.96) | L3MBTL1HRH3ACHE | |
| SCHEMBL17525770 | 0.71 | MEN1 (0.44) | — | |
| SCHEMBL13534477 | 0.70 | L3MBTL1 (0.70) | L3MBTL1HRH3ACHE | |
| SCHEMBL1626076 | 0.70 | L3MBTL1 (1.00) | L3MBTL1HRH3ACHE | |
| SCHEMBL12947867 | 0.70 | L3MBTL1 (0.70) | L3MBTL1HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992441-A | 1-[[5-[[4-substituted-1-piperazinyl]methyl]-pyrrol-2-yl or furan-2-yl]methyl-2-piperidinones useful in treating schizophrenia | MCNEILAB, INC. (US) | 1991-02-12 | — | — | US | claimed |
| US-4992441-A | 1-[[5-[[4-substituted-1-piperazinyl]methyl]-pyrrol-2-yl or furan-2-yl]methyl-2-piperidinones useful in treating schizophrenia | MCNEILAB, INC. (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0312345-A2 | 1-(5-(4-substituted-1-piperazinyl)methyl)-pyrrol-2-yl or furan-2-yl)methyl-2-piperidinones useful in treating schizophrenia | MCNEILAB, INC. (US) | 1989-04-19 | — | — | EP | disclosed |