SCHEMBL9751075

SCHEMBL9751075

BrCCc1c(Br)cc(Br)c(Oc2c(Br)cc(Br)c(CCBr)c2Br)c1Br

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.34
CA4 P22748 2/20 0.34
CA1 P00915 1/20 0.33
CA6 P23280 1/20 0.33
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9751154 0.82 CA2 (0.33) CA2CA4CA1CA6ALOX15
SCHEMBL8516055 0.73 ALDH1A1 (0.38) CA2CA4CA1CA6
SCHEMBL31497689 0.73 ALDH1A1 (0.38) CA2CA4CA1CA6
SCHEMBL6317714 0.72 CA2 (0.32) CA2CA4CA1CA6
SCHEMBL16678495 0.69 CA2 (0.50) CA2CA4CA1CA6ALOX15
SCHEMBL21869865 0.69 CA2 (0.34) CA2CA4CA1CA6
SCHEMBL10831889 0.68 LMNA (0.32)
SCHEMBL10454321 0.67 TDP1 (0.39)
SCHEMBL16678555 0.66 TDP1 (0.50) CA2CA4CA1CA6ALOX15
SCHEMBL10830904 0.64 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0388445-A4 FLAME RETARDANT HIGHER ALKYL BISPHENOXY ALKANES AND THEIR APPLICATION TO ABS POLYMER SYSTEMS 1991-07-03 EP disclosed
EP-0388445-A1 FLAME RETARDANT HIGHER ALKYL BISPHENOXY ALKANES AND THEIR APPLICATION TO ABS POLYMER SYSTEMS GREAT LAKES CHEMICAL CORPORATION (US) 1990-09-26 EP disclosed
WO-1990000165-A1 FLAME RETARDANT HIGHER ALKYL BISPHENOXY ALKANES AND THEIR APPLICATION TO ABS POLYMER SYSTEMS GREAT LAKES CHEMICAL CORPORATION (US) 1990-01-11 WO disclosed
US-4891449-A FIREPROOFING PLASTICS GREAT LAKES CHEMICAL CORPORATION (US) 1990-01-02 US disclosed