Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.37 |
| ▸ | PYGL | P06737 | 3/20 | 0.37 |
| ▸ | PYGM | P11217 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742729 | 0.93 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL2353972 | 0.93 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL11913232 | 0.93 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL9708959 | 0.93 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL5822927 | 0.78 | PYGB (0.35) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL27619105 | 0.77 | PYGB (0.41) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL23017509 | 0.76 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL17565535 | 0.76 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL16389053 | 0.76 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL29223633 | 0.76 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364559-A4 | SUBSTITUTED ADENINE DERIVATIVES USEFUL AS THERAPEUTIC AGENTS | — | 1991-01-09 | — | — | EP | disclosed |
| EP-0364559-A1 | SUBSTITUTED ADENINE DERIVATIVES USEFUL AS THERAPEUTIC AGENTS. | SCRIPPS CLINIC RES (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989008658-A1 | SUBSTITUTED ADENINE DERIVATIVES USEFUL AS THERAPEUTIC AGENTS | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1989-09-21 | — | — | WO | disclosed |