Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808045 | 0.83 | HIF1A (0.34) | POLBMAPTMEN1NPC1RAB9A | |
| SCHEMBL9751536 | 0.75 | MAOB (0.33) | — | |
| SCHEMBL11102997 | 0.74 | MDM2 (0.32) | — | |
| SCHEMBL1682170 | 0.73 | HIF1A (0.33) | POLBMAPTMEN1NPC1RAB9A | |
| SCHEMBL9751489 | 0.71 | — | — | |
| SCHEMBL9094342 | 0.70 | MDM2 (0.35) | MEN1KMT2A | |
| SCHEMBL7638594 | 0.69 | HIF1A (0.37) | POLBMAPTMEN1NPC1RAB9A | |
| SCHEMBL8982590 | 0.68 | ALDH1A1 (0.36) | POLBMAPTNPC1RAB9AKMT2A | |
| SCHEMBL3984769 | 0.68 | ALDH1A1 (0.36) | POLBMAPTNPC1RAB9AKMT2A | |
| SCHEMBL27513097 | 0.68 | ALDH1A1 (0.36) | POLBMAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428605-A1 | SYNTHETIC RECEPTOR ANALOGUES. | SYMBICOM AB (SE) | 1991-05-29 | — | — | EP | disclosed |
| WO-1990001488-A1 | SYNTHETIC RECEPTOR ANALOGUES | SYMBICOM AKTIEBOLAG (SE) | 1990-02-22 | — | — | WO | disclosed |