Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27513097 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP3A4HIF1AEPAS1TSHR | |
| SCHEMBL27513098 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP3A4HIF1AEPAS1TSHR | |
| SCHEMBL8982590 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP3A4HIF1AEPAS1TSHR | |
| SCHEMBL9251530 | 0.89 | LMNA (0.31) | LMNA | |
| SCHEMBL7638594 | 0.88 | HIF1A (0.37) | ALDH1A1CYP3A4HIF1AEPAS1TSHR | |
| SCHEMBL28945305 | 0.79 | CES1 (0.37) | ALDH1A1CYP3A4HIF1AEPAS1TSHR | |
| SCHEMBL10399320 | 0.78 | CES2 (0.36) | ALDH1A1HIF1AEPAS1CES2LMNA | |
| SCHEMBL10399319 | 0.78 | CES2 (0.36) | ALDH1A1HIF1AEPAS1CES2LMNA | |
| SCHEMBL11383230 | 0.78 | LMNA (0.36) | ALDH1A1HIF1AEPAS1CES2LMNA | |
| Hydrochloric Acid SCHEMBL28792392 | 0.78 | CES2 (0.36) | ALDH1A1HIF1AEPAS1CES2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709057-A1 | SYNTHESIS OF SPONGOSINE | Cambridge Biotechnology Ltd (GB) | 2006-10-11 | — | — | EP | claimed |
| WO-2005070947-A1 | SYNTHESIS OF SPONGOSINE | CAMBRIDGE BIOTECHNOLOGY LIMITED (GB) | 2005-08-04 | — | — | WO | claimed |
| WO-2009058800-A2 | SYNTHESIS OF NUCLEOSIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-05-07 | — | — | WO | disclosed |
| EP-0065324-A1 | 1,3-Diazepine compounds | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1982-11-24 | — | — | EP | disclosed |
| EP-0034424-A2 | Seven-membered ring compounds as inhibitors of cytidine deaminase | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1981-08-26 | — | — | EP | disclosed |
| WO-1981002164-A1 | SEVEN-MEMBERED RING COMPOUNDS AS INHIBITORS OF CYTIDINE DEAMINASE | US COMMERCE (US) | 1981-08-06 | — | — | WO | disclosed |
| US-4275057-A | CANCER AND ANTITUMOR DRUG RESEARCH | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1981-06-23 | — | — | US | disclosed |