Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862745 | 0.81 | ACACB (0.50) | FDPSCYP1A2TBXAS1CYP3A4PKM | |
| SCHEMBL6852331 | 0.80 | TAAR1 (0.53) | CYP2D6CYP1A2CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL1310109 | 0.80 | TAAR1 (0.53) | CYP2D6CYP1A2CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL1086155 | 0.80 | TAAR1 (0.53) | CYP2D6CYP1A2CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL9770952 | 0.79 | FDPS (0.54) | FDPSCYP2D6CYP1A2TBXAS1CYP3A4 | |
| SCHEMBL12606607 | 0.77 | TAAR1 (0.60) | FDPSCYP2D6CYP1A2TBXAS1CYP3A4 | |
| SCHEMBL4093741 | 0.76 | CTSC (0.55) | FDPSCYP1A2CYP3A4PKMKMT2A | |
| SCHEMBL24521954 | 0.76 | CYP2D6 (0.48) | FDPSCYP2D6CYP1A2TBXAS1CYP3A4 | |
| SCHEMBL1696723 | 0.76 | FDPS (0.51) | FDPSCYP2D6CYP1A2TBXAS1CYP3A4 | |
| SCHEMBL694048 | 0.76 | FDPS (0.51) | FDPSCYP2D6CYP1A2TBXAS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400065-A4 | LHRH ANALOGS | — | 1991-03-13 | — | — | EP | claimed |
| EP-0413209-A1 | LHRH analogs | TAP Pharmaceuticals Inc. (US) | 1991-02-20 | — | — | EP | claimed |
| EP-0400065-A1 | LHRH ANALOGS. | ABBOTT LAB (US) | 1990-12-05 | — | — | EP | claimed |
| WO-1989007450-A1 | LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1989-08-24 | — | — | WO | claimed |
| EP-0328090-A2 | LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |