Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694048 | 0.81 | FDPS (0.51) | FDPSNAPRTCYP1A2CYP2D6CHRNA7 | |
| SCHEMBL1696723 | 0.81 | FDPS (0.51) | FDPSNAPRTCYP1A2CYP2D6CHRNA7 | |
| SCHEMBL2264768 | 0.81 | FDPS (0.51) | FDPSNAPRTCYP1A2CYP2D6CHRNA7 | |
| SCHEMBL9751597 | 0.79 | FDPS (0.49) | FDPSNAPRTCYP1A2CYP2D6CHRNB2 | |
| SCHEMBL1697450 | 0.74 | CYP1A2 (0.48) | CYP1A2CYP2A6 | |
| SCHEMBL28748304 | 0.74 | KDM4E (0.50) | FDPSNAPRTCYP1A2KDM4ETBXAS1 | |
| SCHEMBL27652212 | 0.74 | FDPS (0.55) | FDPSNAPRTCYP1A2CYP2D6CHRNA7 | |
| SCHEMBL103883 | 0.74 | FDPS (0.55) | FDPSCYP1A2CYP2D6CHRNA7CHRNB2 | |
| SCHEMBL272334 | 0.74 | — | — | |
| SCHEMBL9547411 | 0.74 | FDPS (0.59) | FDPSNAPRTCYP1A2CYP2D6CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045537-A | Treating Diseases Caused by Retroviruses | SANDOZ LTD. (CH) | 1991-09-03 | — | — | US | disclosed |
| EP-0387309-A1 | RENIN INHIBITORS, PROCESS FOR PRODUCING THEM AND USE THEREOF | SANDOZ AG (CH) | 1990-09-19 | — | — | EP | disclosed |
| WO-1989010917-A2 | RENIN INHIBITORS, PROCESS FOR PRODUCING THEM AND USE THEREOF | SANDOZ AG (CH) | 1989-11-16 | — | — | WO | disclosed |