⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534735 | 0.85 | DNM1 (0.33) | — | |
| SCHEMBL10703861 | 0.83 | GPR84 (0.39) | — | |
| SCHEMBL514687 | 0.83 | — | — | |
| SCHEMBL7746403 | 0.81 | GPR84 (0.42) | — | |
| SCHEMBL6743046 | 0.81 | GPR84 (0.42) | — | |
| SCHEMBL1276926 | 0.81 | GPR84 (0.42) | — | |
| SCHEMBL7746400 | 0.81 | GPR84 (0.42) | — | |
| SCHEMBL6738137 | 0.81 | GPR84 (0.42) | — | |
| SCHEMBL6021146 | 0.81 | GPR84 (0.42) | — | |
| SCHEMBL8971316 | 0.81 | GPR84 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422119-A4 | BENZOTHIOPHENE DERIVATIVES USEFUL FOR MODIFYING FEEDING BEHAVIOR AND OBSESSIVE-COMPULSIVE BEHAVIOR | — | 1991-11-13 | — | — | EP | disclosed |
| EP-0422119-A1 | BENZOTHIOPHENE DERIVATIVES USEFUL FOR MODIFYING FEEDING BEHAVIOR AND OBSESSIVE-COMPULSIVE BEHAVIOR | NEUREX CORPORATION (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4978669-A | ALTERING MACRONUTRIENT PREFERENCE | NEUREX CORPORATION (US) | 1990-12-18 | — | — | US | disclosed |
| WO-1989012447-A1 | BENZOTHIOPHENE DERIVATIVES USEFUL FOR MODIFYING FEEDING BEHAVIOR AND OBSESSIVE-COMPULSIVE BEHAVIOR | NEUREX CORPORATION (US) | 1989-12-28 | — | — | WO | disclosed |
| US-4833236-A | Erythromycin derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0245013-A1 | Erythromycin derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1987-11-11 | — | — | EP | disclosed |
| EP-0034700-A1 | Salts of erythromycin A esters and preparation process | ABBOTT LABORATORIES (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4264765-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1981-04-28 | — | — | US | disclosed |