Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | OGT | O15294 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751642 | 1.00 | LMNA (0.44) | LMNAKDM4ENPSR1MMP2MMP9 | |
| SCHEMBL7401749 | 0.77 | KDM4E (0.38) | LMNAKDM4EOGTUSP2MAPT | |
| SCHEMBL19582927 | 0.69 | LMNA (0.47) | LMNAKDM4ENPSR1MMP2MMP9 | |
| SCHEMBL4562956 | 0.65 | C3AR1 (0.53) | LMNAKDM4ENPSR1MMP2MMP9 | |
| SCHEMBL28296892 | 0.64 | KDM4E (0.50) | LMNAKDM4ENPSR1 | |
| SCHEMBL28150934 | 0.63 | TSHR (0.41) | LMNAMMP2MMP9MMP3MMP8 | |
| SCHEMBL10995850 | 0.60 | — | — | |
| SCHEMBL10995851 | 0.60 | — | — | |
| SCHEMBL11860484 | 0.60 | KDM4E (0.38) | KDM4EOGTUSP2MAPTRECQL | |
| SCHEMBL11860477 | 0.60 | KDM4E (0.38) | KDM4EOGTUSP2MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066785-A | CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING | CITY OF HOPE (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0407527-A4 | CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING | — | 1991-10-30 | — | — | EP | disclosed |
| EP-0407527-A1 | CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING | CITY OF HOPE (US) | 1991-01-16 | — | — | EP | disclosed |
| WO-1990005739-A1 | CARBOXYL TERMINAL PEPTIDE AND PROTEIN SEQUENCING | MILLER CHAD G (US) | 1990-05-31 | — | — | WO | disclosed |