Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinimide SCHEMBL7039031 | 0.77 | CRBN (0.61) | KDM4ELMNACRBNALDH1A1CYP19A1 | |
| Succinimide SCHEMBL27423831 | 0.77 | CRBN (0.61) | KDM4ELMNACRBNALDH1A1CYP19A1 | |
| Hexadecane SCHEMBL28112342 | 0.75 | CRBN (0.58) | KDM4ELMNACRBNALDH1A1THRB | |
| Dodecane SCHEMBL27509294 | 0.75 | CRBN (0.58) | KDM4ELMNACRBNALDH1A1THRB | |
| SCHEMBL19582927 | 0.75 | LMNA (0.47) | KDM4ELMNANPSR1FAAHMGLL | |
| Succinimide SCHEMBL27884254 | 0.74 | CRBN (0.50) | KDM4ELMNACRBNALDH1A1CYP19A1 | |
| SCHEMBL16178828 | 0.74 | KDM4E (0.71) | KDM4ELMNANPSR1FAAHMGLL | |
| Succinimide SCHEMBL4639601 | 0.73 | CRBN (0.61) | KDM4ELMNACRBNCYP19A1ALOX5 | |
| Tetrabuthylammonium SCHEMBL2230716 | 0.68 | SLC22A1 (0.52) | CRBNALDH1A1ALOX5 | |
| Succinimide SCHEMBL18205015 | 0.68 | DNM1 (0.50) | CRBNALDH1A1CYP19A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879888-A | A kind of Fu Ruide carbazole alkali Class A compound and preparation method thereof and application | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2019-06-14 | — | — | CN | claimed |
| CN-109796461-A | A kind of preparation process of Tadalafei impurity I | 杭州康本医药科技有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-107365239-B | A kind of synthetic method of arylalkyne halogen | 华中农业大学 | 2019-08-23 | — | — | CN | disclosed |
| CN-109879888-A | A kind of Fu Ruide carbazole alkali Class A compound and preparation method thereof and application | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2019-06-14 | — | — | CN | disclosed |