Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172657 | 0.83 | LMNA (0.53) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL269329 | 0.77 | LMNA (0.80) | LMNAMAPTPOLBPKMELANE | |
| Lithium SCHEMBL30522746 | 0.75 | LMNA (0.76) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL14760365 | 0.75 | LMNA (0.76) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL9764749 | 0.74 | ALDH1A1 (0.36) | MAPTALDH1A1KMT2AHPGDRAB9A | |
| Phosphine SCHEMBL27576228 | 0.71 | LMNA (0.95) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL660921 | 0.71 | LMNA (0.64) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL24435576 | 0.71 | LMNA (0.70) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL9760958 | 0.71 | LMNA (0.70) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL9325116 | 0.71 | LMNA (0.70) | LMNAMAPTPOLBPKMELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428709-A1 | REACTIVE COMPOUNDS CONTAINING PERFLUOROVINYL GROUPS. | DOW CHEMICAL CO (US) | 1991-05-29 | — | — | EP | disclosed |
| WO-1990015042-A2 | REACTIVE COMPOUNDS CONTAINING PERFLUOROVINYL GROUPS | THE DOW CHEMICAL COMPANY (US) | 1990-12-13 | — | — | WO | disclosed |