Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752087 | 1.00 | SCN9A (0.48) | SCN9AESR1LMNASMN1; SMN2KDM4E | |
| SCHEMBL9752071 | 0.81 | POLB (0.52) | SCN9ALMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL9587283 | 0.77 | RAB9A (0.52) | SCN9ALMNASMN1; SMN2MAPTLIPE | |
| SCHEMBL9397562 | 0.75 | SMN1; SMN2 (0.48) | SCN9ALMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL9194781 | 0.75 | SMN1; SMN2 (0.48) | SCN9ALMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL10564546 | 0.74 | KMT2A (0.48) | SCN9ALMNASMN1; SMN2KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10564555 | 0.74 | SMN1; SMN2 (0.47) | SCN9ALMNASMN1; SMN2KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10564552 | 0.74 | SMN1; SMN2 (0.47) | SCN9ALMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL9359751 | 0.74 | LMNA (0.49) | SCN9ALMNASMN1; SMN2MAPTLIPE | |
| SCHEMBL10423962 | 0.74 | SMN1; SMN2 (0.49) | SCN9ALMNASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015123-A1 | SUBSTITUTED CYCLOHEXANEDIONES AND THEIR HERBICIDAL USES | DOWELANCO (US) | 1991-10-17 | — | — | WO | disclosed |
| EP-0449385-A2 | Substituted cyclohexanediones and their herbicidal uses | DOWELANCO (US) | 1991-10-02 | — | — | EP | disclosed |
| US-4983211-A | Substituted cyclohexanediones and their herbicidal use | DOWELANCO (US) | 1991-01-08 | — | — | US | disclosed |