Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945622 | 0.85 | SMN1; SMN2 (0.62) | POLBCASP6ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9752087 | 0.81 | SCN9A (0.48) | SMN1; SMN2KDM4ESCN9ALMNAMAPT | |
| SCHEMBL9752086 | 0.81 | SCN9A (0.48) | SMN1; SMN2KDM4ESCN9ALMNAMAPT | |
| SCHEMBL9587283 | 0.81 | RAB9A (0.52) | ALDH1A1SMN1; SMN2SCN9ALMNAHTT | |
| SCHEMBL30879505 | 0.78 | KIF11 (0.44) | POLBCASP6ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL876197 | 0.77 | ALDH1A1 (0.65) | POLBALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL876592 | 0.77 | ALDH1A1 (0.59) | POLBCASP6ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL875765 | 0.76 | ALDH1A1 (0.41) | POLBCASP6ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL4824833 | 0.75 | ALDH1A1 (0.63) | POLBALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL15814057 | 0.75 | ALDH1A1 (0.49) | POLBCASP6ALDH1A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015123-A1 | SUBSTITUTED CYCLOHEXANEDIONES AND THEIR HERBICIDAL USES | DOWELANCO (US) | 1991-10-17 | — | — | WO | disclosed |
| EP-0449385-A2 | Substituted cyclohexanediones and their herbicidal uses | DOWELANCO (US) | 1991-10-02 | — | — | EP | disclosed |
| US-4983211-A | Substituted cyclohexanediones and their herbicidal use | DOWELANCO (US) | 1991-01-08 | — | — | US | disclosed |