Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.57 |
| ▸ | DRD3 | P35462 | 4/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722643 | 0.93 | OPRK1 (0.57) | DRD2DRD3PLAUMAPTOPRK1 | |
| SCHEMBL2724775 | 0.93 | OPRK1 (0.57) | DRD2DRD3PLAUMAPTOPRK1 | |
| SCHEMBL29593839 | 0.85 | PNMT (0.49) | DRD2DRD3PNMTOPRK1KDM1A | |
| SCHEMBL4735015 | 0.85 | PNMT (0.49) | DRD2DRD3PNMTOPRK1KDM1A | |
| Hydrochloric Acid SCHEMBL1785634 | 0.84 | PNMT (0.47) | DRD2DRD3PNMTKDM1A | |
| Hydrochloric Acid SCHEMBL29878547 | 0.84 | PNMT (0.47) | DRD2DRD3PNMTKDM1A | |
| SCHEMBL17478464 | 0.77 | OPRK1 (0.48) | OPRK1 | |
| SCHEMBL17478461 | 0.77 | OPRK1 (0.48) | OPRK1 | |
| SCHEMBL23652645 | 0.76 | DRD2 (0.45) | DRD2DRD3PNMTACHE | |
| SCHEMBL22070979 | 0.76 | PNMT (0.45) | DRD2DRD3PNMTKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435988-A1 | 2-AMINO-7-CARBAMOYL-1,2,3,4-TETRAHYDRONAPHTHALENES, PROCESS FOR PREPARING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM KG (DE) | 1991-07-10 | — | — | EP | claimed |
| WO-1991001297-A1 | 2-AMINO-7-CARBAMOYL-1,2,3,4-TETRAHYDRONAPHTHALENES, PROCESS FOR PREPARING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM KG (DE) | 1991-02-07 | — | — | WO | claimed |