Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 2/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TPO | P07202 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | EPX | P11678 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752226 | 1.00 | MGMT (0.34) | MGMTPDE2AMPOHSPA5CTSL | |
| SCHEMBL9752163 | 0.87 | MGMT (0.39) | MGMTPDE2AHSPA5NT5E | |
| SCHEMBL9752214 | 0.78 | ABCB1 (0.43) | MGMTPDE2AMPOTPOCYP3A4 | |
| SCHEMBL9752237 | 0.78 | ABCB1 (0.43) | MGMTPDE2AMPOTPOCYP3A4 | |
| SCHEMBL9752215 | 0.78 | ABCB1 (0.43) | MGMTPDE2AMPOTPOCYP3A4 | |
| SCHEMBL9752228 | 0.73 | MGMT (0.36) | MGMTMPOTPOCYP3A4EPX | |
| SCHEMBL9752212 | 0.72 | PDE2A (0.49) | PDE2ANT5E | |
| SCHEMBL10171925 | 0.72 | PDE2A (0.44) | MGMTPDE2AMPOCYP1A2TSHR | |
| SCHEMBL9366104 | 0.72 | AHCY (0.48) | MGMTPDE2AMPOTPOCYP3A4 | |
| SCHEMBL9366097 | 0.72 | AHCY (0.48) | MGMTPDE2AMPOTPOCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001318-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1991-02-07 | — | — | WO | disclosed |