Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19697582 | 1.00 | SIGMAR1 (0.65) | SIGMAR1CYP2D6CYP1A2CYP2C19ADRB2 | |
| SCHEMBL8092817 | 0.86 | SIGMAR1 (0.72) | SIGMAR1ADRB2ADORA3CHRM1ADRA2B | |
| SCHEMBL23763884 | 0.85 | CYP1A2 (0.68) | SIGMAR1CYP2D6CYP1A2CYP2C19HRH3 | |
| SCHEMBL28041371 | 0.83 | LPL (0.59) | TAAR1 | |
| SCHEMBL8780379 | 0.83 | LPL (0.59) | TAAR1 | |
| SCHEMBL11069727 | 0.83 | LPL (0.59) | TAAR1 | |
| SCHEMBL9485795 | 0.83 | LPL (0.59) | TAAR1 | |
| SCHEMBL105418 | 0.83 | LPL (0.59) | TAAR1 | |
| SCHEMBL11073651 | 0.83 | LPL (0.59) | TAAR1 | |
| SCHEMBL6357798 | 0.83 | SIGMAR1 (0.63) | SIGMAR1CYP2D6CYP1A2CYP2C19ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462262-A1 | COPOLYMERIZED METHINE COLORANT-POLYESTER COLOR CONCENTRATES | EASTMAN CHEMICAL COMPANY (US) | 1991-12-27 | — | — | EP | disclosed |
| WO-1991010693-A1 | COPOLYMERIZED METHINE COLORANT-POLYESTER COLOR CONCENTRATES | EASTMAN KODAK COMPANY (US) | 1991-07-25 | — | — | WO | disclosed |