Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679224 | 0.81 | RIPK1 (0.54) | RIPK1GAACACNA1HLMNAKIF11 | |
| SCHEMBL9676881 | 0.81 | RIPK1 (0.59) | RIPK1GAACACNA1HLMNAKIF11 | |
| SCHEMBL9678365 | 0.80 | RIPK1 (0.56) | RIPK1GAACACNA1HLMNAKIF11 | |
| SCHEMBL9678615 | 0.77 | RIPK1 (0.57) | RIPK1GAACACNA1HLMNAKIF11 | |
| SCHEMBL9397457 | 0.77 | RIPK1 (0.49) | RIPK1GAACACNA1HLMNAKIF11 | |
| SCHEMBL9678604 | 0.76 | RIPK1 (0.56) | RIPK1GAACACNA1HLMNAKIF11 | |
| SCHEMBL9678631 | 0.76 | RIPK1 (0.56) | RIPK1GAACACNA1HLMNAKIF11 | |
| SCHEMBL9676937 | 0.76 | RIPK1 (0.53) | RIPK1GAACACNA1HLMNAKIF11 | |
| SCHEMBL9676048 | 0.73 | RIPK1 (0.56) | RIPK1GAACACNA1HLMNAKIF11 | |
| SCHEMBL9676811 | 0.73 | RIPK1 (0.56) | RIPK1GAACACNA1HLMNABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3173884-A | — | — | None | — | — | JP | disclosed |
| JP-H03173884-A | IMIDAZOLESULFONAMIDE AND HERBICIDE | NISSAN CHEM IND LTD | 1991-07-29 | — | — | JP | disclosed |