Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973523 | 0.81 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1BCHEMEN1KMT2A | |
| SCHEMBL13503770 | 0.73 | ALDH1A1 (0.70) | SIGMAR1ALDH1A1TSHRHSD11B1LMNA | |
| SCHEMBL9891794 | 0.73 | SIGMAR1 (0.60) | SIGMAR1BCHE | |
| SCHEMBL24276406 | 0.71 | SIGMAR1 (0.57) | SIGMAR1BCHE | |
| SCHEMBL20315424 | 0.71 | ALDH1A1 (0.67) | SIGMAR1ALDH1A1TSHRHSD11B1LMNA | |
| SCHEMBL942700 | 0.70 | SIGMAR1 (0.57) | SIGMAR1BCHE | |
| SCHEMBL10559542 | 0.69 | ALDH1A1 (1.00) | ALDH1A1TSHRTP53HSD11B1LMNA | |
| SCHEMBL7131881 | 0.69 | ALDH1A1 (1.00) | ALDH1A1TSHRTP53HSD11B1LMNA | |
| SCHEMBL942650 | 0.68 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1TSHRTP53HSD11B1 | |
| SCHEMBL19004863 | 0.68 | ALDH1A1 (0.61) | SIGMAR1ALDH1A1TSHRHSD11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |