Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7584780 | 0.75 | KMT2A (0.46) | MEN1KMT2AALDH1A1GAACXCR2 | |
| SCHEMBL27796629 | 0.73 | MAPT (0.42) | MAPK1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL9844488 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HPGDPPARGHTTNPC1 | |
| SCHEMBL679864 | 0.71 | RAB9A (0.47) | ALDH1A1GAAHPGDSMN1; SMN2HTT | |
| SCHEMBL7561830 | 0.71 | RAB9A (0.47) | ALDH1A1GAAHPGDSMN1; SMN2HTT | |
| SCHEMBL27732526 | 0.68 | TDP1 (0.53) | MEN1KMT2AALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL8365590 | 0.67 | CYP1A2 (0.39) | MEN1KMT2AALDH1A1CYP2C19GAA | |
| SCHEMBL20999769 | 0.67 | RAB9A (0.50) | MAPK1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL12984801 | 0.66 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1CYP2C9HPGD | |
| SCHEMBL20334271 | 0.66 | KMT2A (0.53) | MAPK1MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000923-A2 | PROCESS FOR PRODUCING ANTIBACTERIAL INTERMEDIATES VIA ENZYME HYDROLYSIS OF RACEMIC SUBSTRATES | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | disclosed |
| EP-0407190-A2 | Process for producing antibacterial intermediates via enzyme hydrolysis of racemic substrates | SCHERING CORPORATION (US) | 1991-01-09 | — | — | EP | disclosed |
| EP-0405104-A1 | Process for preparing antibacterial compounds and intermediates thereto | SCHERING CORPORATION (US) | 1991-01-02 | — | — | EP | disclosed |
| WO-1990014434-A1 | PROCESS FOR PREPARING ANTIBACTERIAL COMPOUNDS AND INTERMEDIATES THERETO | SCHERING CORPORATION (US) | 1990-11-29 | — | — | WO | disclosed |