Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 8/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679864 | 0.84 | RAB9A (0.47) | ALDH1A1LMNAMAPTPKMHTT | |
| SCHEMBL7561830 | 0.84 | RAB9A (0.47) | ALDH1A1LMNAMAPTPKMHTT | |
| SCHEMBL28335088 | 0.78 | LMNA (0.40) | ALDH1A1LMNAMAPTPKMHTT | |
| SCHEMBL7576033 | 0.76 | L3MBTL1 (0.42) | ALDH1A1LMNAMAPTPKMHTT | |
| SCHEMBL27873589 | 0.74 | MAPT (0.49) | ALDH1A1LMNAMAPTPKMHTT | |
| SCHEMBL9638522 | 0.73 | RAB9A (0.46) | ALDH1A1LMNAMAPTPKMHTT | |
| SCHEMBL2322993 | 0.73 | RAB9A (0.46) | ALDH1A1LMNAMAPTPKMHTT | |
| SCHEMBL9504877 | 0.73 | MEN1 (0.39) | ALDH1A1LMNAMAPTPKMHTT | |
| SCHEMBL2159580 | 0.73 | MEN1 (0.39) | ALDH1A1LMNAMAPTPKMHTT | |
| SCHEMBL421667 | 0.73 | MEN1 (0.39) | ALDH1A1LMNAMAPTPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405104-A1 | Process for preparing antibacterial compounds and intermediates thereto | SCHERING CORPORATION (US) | 1991-01-02 | — | — | EP | disclosed |