Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752490 | 0.95 | ALDH1A1 (0.34) | ALDH1A1LMNALPAR3LPAR2CYP3A4 | |
| SCHEMBL9752493 | 0.90 | ALDH1A1 (0.30) | ALDH1A1LMNA | |
| SCHEMBL20211357 | 0.85 | NAAA (0.35) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL1630028 | 0.80 | NAAA (0.44) | ALDH1A1LMNACYP3A4TSHRATM | |
| SCHEMBL11710524 | 0.79 | NAAA (0.47) | ALDH1A1LMNATSHR | |
| SCHEMBL1421042 | 0.79 | NAAA (0.47) | ALDH1A1LMNATSHR | |
| SCHEMBL8416800 | 0.79 | NAAA (0.47) | ALDH1A1LMNATSHR | |
| SCHEMBL28506895 | 0.79 | NAAA (0.47) | ALDH1A1LMNATSHR | |
| SCHEMBL492248 | 0.78 | TSHR (0.36) | ALDH1A1CYP3A4TSHRMAPTSMN1; SMN2 | |
| SCHEMBL28856839 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNATSHRSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000300-A1 | (CO)POLYMER MODIFICATION EMPLOYING UNSATURATED t-ALKYL PEROXY ALKENES | AKZO N.V. (NL) | 1991-01-10 | — | — | WO | disclosed |