Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762604 | 0.80 | ESR1 (0.51) | KMT2AMAPTSMN1; SMN2SLC6A3PKM | |
| SCHEMBL11252807 | 0.78 | KMT2A (0.52) | KMT2AMAPTSMN1; SMN2SLC6A3PKM | |
| SCHEMBL6761214 | 0.78 | SLC6A3 (0.58) | KMT2AMAPTSMN1; SMN2SLC6A3PKM | |
| Acetic Acid SCHEMBL29588064 | 0.76 | KMT2A (0.68) | KMT2AMAPTSMN1; SMN2SLC6A3PKM | |
| SCHEMBL5551848 | 0.75 | LMNA (0.64) | KMT2AMAPTSMN1; SMN2SLC6A3PKM | |
| SCHEMBL6767307 | 0.75 | KMT2A (0.47) | KMT2AMAPTSMN1; SMN2SLC6A3GAA | |
| SCHEMBL3826754 | 0.74 | KMT2A (0.66) | KMT2AMAPTSMN1; SMN2SLC6A3ESR1 | |
| SCHEMBL6764011 | 0.74 | MAPT (0.55) | KMT2AMAPTSMN1; SMN2SLC6A3ESR1 | |
| SCHEMBL26490187 | 0.74 | SLC6A3 (0.72) | KMT2AMAPTSMN1; SMN2SLC6A3ESR1 | |
| SCHEMBL725404 | 0.73 | KMT2A (0.76) | KMT2AMAPTSMN1; SMN2SLC6A3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009595-A1 | ANTI-VIRAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |