Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.55 |
| ▸ | BCL2 | P10415 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.44 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457057 | 0.84 | SLC5A1 (0.65) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL10908531 | 0.81 | LMNA (0.56) | LMNABCL2L1BCL2MCL1MAPT | |
| SCHEMBL10908527 | 0.78 | LMNA (0.52) | LMNABCL2L1BCL2MCL1MAPT | |
| SCHEMBL145265 | 0.78 | LMNA (0.78) | LMNABCL2L1BCL2MCL1MAPT | |
| SCHEMBL17718212 | 0.77 | LMNA (0.55) | LMNABCL2L1BCL2MCL1MAPT | |
| SCHEMBL29585980 | 0.77 | LMNA (0.77) | LMNABCL2L1BCL2MCL1MAPT | |
| SCHEMBL11566548 | 0.77 | LMNA (1.00) | LMNABCL2L1BCL2MCL1MAPT | |
| SCHEMBL28618526 | 0.76 | BCL2L1 (0.50) | LMNABCL2L1BCL2MCL1MAPT | |
| SCHEMBL20556449 | 0.75 | CYP3A4 (0.59) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL6245947 | 0.75 | MEN1 (0.68) | LMNABCL2L1BCL2MCL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009595-A1 | ANTI-VIRAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |