Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209958 | 0.83 | L3MBTL1 (0.42) | L3MBTL1KDM4EALDH1A1POLBSLC6A2 | |
| SCHEMBL2737127 | 0.80 | L3MBTL1 (0.47) | L3MBTL1KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7768141 | 0.79 | CA1 (0.39) | MAOBPPARGPPARA | |
| SCHEMBL8709433 | 0.79 | L3MBTL1 (0.50) | L3MBTL1KDM4EALDH1A1POLBSLC6A2 | |
| SCHEMBL30620488 | 0.77 | ACHE (0.48) | L3MBTL1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14661889 | 0.77 | ACHE (0.44) | ALDH1A1MAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11527555 | 0.76 | KIF11 (0.51) | L3MBTL1KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10345195 | 0.75 | TSHR (0.44) | L3MBTL1KDM4EALDH1A1POLBSLC6A2 | |
| SCHEMBL11662822 | 0.75 | MAOB (0.41) | L3MBTL1KDM4EALDH1A1POLBSLC6A2 | |
| SCHEMBL15146324 | 0.75 | L3MBTL1 (0.50) | L3MBTL1KDM4EALDH1A1POLBSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009031-A1 | TRIFLUOROMETHYL SUBSTITUTED COMPOUNDS AND A PHARMACEUTICAL COMPOSITION | BEECHAM GROUP PLC (GB) | 1991-06-27 | — | — | WO | disclosed |