SCHEMBL9752879

SCHEMBL9752879

CCCCC(CC)Cc1cccc2c1Cc1ccccc1OC(C(=O)O)O2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
CA2 P00918 1/20 0.35
CYP3A4 P08684 1/20 0.35
MTNR1A P48039 4/20 0.34
MTNR1B P49286 4/20 0.34
LMNA P02545 2/20 0.34
TSHR P16473 2/20 0.34
MAPK1 P28482 1/20 0.34
PDE2A O00408 1/20 0.33
HDAC3 O15379 3/20 0.33
HDAC1 Q13547 3/20 0.33
HDAC2 Q92769 3/20 0.33
HDAC8 Q9BY41 3/20 0.33
HDAC6 Q9UBN7 3/20 0.33
HDAC4 P56524 2/20 0.33
HDAC7 Q8WUI4 2/20 0.33
HDAC10 Q969S8 2/20 0.33
HDAC11 Q96DB2 2/20 0.33
HDAC9 Q9UKV0 2/20 0.33
HDAC5 Q9UQL6 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9989723 0.78 TSHR (0.38) ALDH1A1CA2CYP3A4LMNATSHR
Zinc Ion SCHEMBL15157996 0.73 TSHR (0.36) ALDH1A1CA2CYP3A4LMNATSHR
SCHEMBL15158109 0.73 CA2 (0.37) ALDH1A1CA2CYP3A4LMNATSHR
Potassium Ion SCHEMBL1913954 0.73 TSHR (0.36) ALDH1A1CA2CYP3A4LMNATSHR
SCHEMBL10399931 0.73 ALDH1A1 (0.52) ALDH1A1CA2CYP3A4LMNATSHR
SCHEMBL14994717 0.73 PNMT (0.50) ALDH1A1CA2CYP3A4LMNATSHR
SCHEMBL10471441 0.72 POLB (0.44) ALDH1A1TSHRMAPK1POLBCASP6
Bicarbonate SCHEMBL17800242 0.72 ALDH1A1 (0.53) ALDH1A1CA2CYP3A4LMNATSHR
SCHEMBL9327125 0.70 POLB (0.56) TSHRHDAC3HDAC1HDAC2HDAC8
SCHEMBL10470758 0.70 POLB (0.44) TSHRHDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991000009-A1 NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES FERMENTA ASC CORPORATION (US) 1991-01-10 WO disclosed