Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 3/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27349905 | 0.86 | PTGER1 (0.38) | DHODHPTGER1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9753357 | 0.84 | PTGER1 (0.36) | DHODHPTGER1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9752927 | 0.82 | PTGER1 (0.41) | DHODHPTGER1ALDH1A1KDM4EHMGCR | |
| SCHEMBL9752983 | 0.81 | GCGR (0.43) | GCGR | |
| SCHEMBL9753644 | 0.81 | PTGS2 (0.36) | ALDH1A1HMGCRKDM5BPTGS2KCNK3 | |
| SCHEMBL27348769 | 0.77 | PTGS2 (0.34) | KDM5BPTGS2 | |
| SCHEMBL9753651 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10HPGDALOX15 | |
| SCHEMBL9752976 | 0.76 | KDM4E (0.43) | ALDH1A1KDM4EHSD17B10HPGDALOX15 | |
| SCHEMBL9752965 | 0.75 | MAPK14 (0.43) | DHODHPTGER1ALDH1A1CYP1A2KDM5B | |
| SCHEMBL9753381 | 0.75 | HMGCR (0.39) | ALDH1A1HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |
| CN-1056690-A | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-12-04 | — | — | CN | disclosed |