Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 5/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | HMGCR | P04035 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27349905 | 0.88 | PTGER1 (0.38) | PTGER1CSNK1DCSNK1EKDM4EALDH1A1 | |
| SCHEMBL9753107 | 0.85 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10PTGS2KMT2A | |
| SCHEMBL9752927 | 0.84 | PTGER1 (0.41) | PTGER1KDM4EALDH1A1DHODHHMGCR | |
| SCHEMBL9753363 | 0.84 | DHODH (0.38) | PTGER1CSNK1DCSNK1EKDM4EALDH1A1 | |
| SCHEMBL9753031 | 0.80 | PPP1CA (0.37) | CSNK1DCSNK1EKDM4EKDM5BDHODH | |
| SCHEMBL9753119 | 0.80 | PTGS2 (0.36) | ALDH1A1KDM5BPTGS2KMT2AKCNK3 | |
| SCHEMBL9752952 | 0.80 | GCGR (0.39) | CSNK1DCSNK1EKDM5BPTGS2PTGS1 | |
| SCHEMBL27389552 | 0.79 | GCGR (0.38) | KDM4EALDH1A1HSD17B10RXFP1APOBEC3G | |
| SCHEMBL9752965 | 0.77 | MAPK14 (0.43) | PTGER1ALDH1A1KDM5BDHODHPTGS2 | |
| SCHEMBL9753463 | 0.76 | PTGS2 (0.34) | KDM5BPTGS2KCNK3MAPK14PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |
| CN-1056690-A | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-12-04 | — | — | CN | disclosed |