Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752976 | 0.88 | KDM4E (0.43) | ALDH1A1KDM4EHPGDLMNAPRKCZ | |
| SCHEMBL9753107 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDLMNAPRKCZ | |
| SCHEMBL9753110 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDLMNAPRKCZ | |
| SCHEMBL5095533 | 0.84 | GCGR (0.42) | ALDH1A1KDM4EHPGDPRKCZGAA | |
| SCHEMBL9753651 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDLMNAPRKCZ | |
| SCHEMBL9752865 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDLMNAPRKCZ | |
| SCHEMBL9753720 | 0.78 | GCGR (0.38) | TGFBR1 | |
| SCHEMBL9752936 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDLMNAPRKCZ | |
| SCHEMBL9752966 | 0.76 | DGAT1 (0.41) | ALDH1A1KDM4EHPGDLMNAPRKCZ | |
| SCHEMBL9752970 | 0.76 | KDM5B (0.34) | ALDH1A1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |