Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753865 | 0.90 | EGFR (0.59) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL9753377 | 0.89 | EGFR (0.44) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL9753347 | 0.86 | PTPRC (0.43) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL9752829 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL14744691 | 0.85 | EGFR (0.65) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL9752979 | 0.85 | KDM4E (0.51) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL9752965 | 0.84 | MAPK14 (0.43) | ALDH1A1MEN1KMT2AEGFRNPSR1 | |
| SCHEMBL9753208 | 0.84 | CDC7 (0.44) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL5093057 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL3821849 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |