Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17040216 | 0.76 | TDP1 (0.52) | LMNAALOX12ADRA1ASMN1; SMN2GRIA1 | |
| SCHEMBL19841642 | 0.76 | LMNA (0.40) | LMNAALOX12ADRA1ASMN1; SMN2GRIA1 | |
| SCHEMBL19639709 | 0.76 | MAPK1 (0.42) | LMNAADRA1AHPGDALDH1A1 | |
| SCHEMBL27999773 | 0.76 | LMNA (0.40) | LMNAALOX12ADRA1ASMN1; SMN2GRIA1 | |
| SCHEMBL1484499 | 0.73 | DRD2 (0.42) | LMNAALOX12ADRA1ASMN1; SMN2KDM4E | |
| SCHEMBL12827188 | 0.72 | SMN1; SMN2 (0.37) | LMNAALOX12ADRA1ASMN1; SMN2GRIA1 | |
| SCHEMBL22873334 | 0.69 | TNKS (0.33) | DAO | |
| SCHEMBL23873408 | 0.69 | LMNA (0.39) | LMNAALOX12ADRA1ASMN1; SMN2GRIA1 | |
| SCHEMBL8768989 | 0.68 | KMT2A (0.43) | LMNAALOX12ADRA1ASMN1; SMN2GRIA1 | |
| SCHEMBL23873406 | 0.68 | GRIA1 (0.42) | LMNAALOX12ADRA1ASMN1; SMN2GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001326-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1991-02-07 | — | — | WO | disclosed |