Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 5/20 | 0.38 |
| ▸ | TK2 | O00142 | 2/20 | 0.38 |
| ▸ | TYMP | P19971 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9910660 | 0.83 | MAPK1 (0.44) | MAPK1HPGDTK1TK2TYMP | |
| SCHEMBL9753003 | 0.76 | LMNA (0.40) | HPGDALDH1A1LMNAADRA1A | |
| SCHEMBL22260407 | 0.76 | MAPK1 (0.42) | MAPK1HPGDTK1TK2TYMP | |
| SCHEMBL20222500 | 0.76 | MAPK1 (0.42) | MAPK1HPGDTK1TK2TYMP | |
| SCHEMBL9021548 | 0.74 | TK1 (0.39) | MAPK1HPGDTK1TK2TYMP | |
| SCHEMBL22020875 | 0.73 | MAPK1 (0.41) | MAPK1HPGDTK1TK2TYMP | |
| SCHEMBL26793575 | 0.73 | MAPK1 (0.41) | MAPK1HPGDTK1TK2TYMP | |
| SCHEMBL27621506 | 0.72 | MAPK1 (0.46) | MAPK1HPGDTK1TYMPALDH1A1 | |
| SCHEMBL22198654 | 0.71 | TK1 (0.39) | MAPK1HPGDTK1TK2TYMP | |
| SCHEMBL21090689 | 0.71 | TK1 (0.39) | MAPK1HPGDTK1TK2TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112933103-B | Cytidine trifluoride and tipyrimidine hydrochloride combination and application | 江苏集萃分子工程研究院有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-112933103-A | Cytidine trifluoride and tipyrimidine hydrochloride combination and application | 江苏集萃分子工程研究院有限公司 | 2021-06-11 | — | — | CN | disclosed |
| US-20170342386-A1 | REPROGRAMMING OF SOMATIC CELLS | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 2017-11-30 | — | — | US | disclosed |