Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29605518 | 0.87 | POLB (0.38) | TSHRSIRT2SIRT1MAPK1 | |
| SCHEMBL9752005 | 0.83 | MAOA (0.42) | MAOAMAOBNISCHGABRA1GABRB2 | |
| SCHEMBL10400577 | 0.79 | ALDH1A1 (0.47) | TSHR | |
| SCHEMBL10400768 | 0.79 | MAOA (0.39) | MAOAMAOBNISCHGABRA1GABRB2 | |
| SCHEMBL9751996 | 0.77 | NISCH (0.53) | MAOAMAOBNISCHGABRA1GABRB2 | |
| SCHEMBL10400578 | 0.77 | ACSL1 (0.40) | MAOAMAOBNISCHGABRA1GABRB2 | |
| SCHEMBL30783522 | 0.77 | HSD11B1 (0.45) | GABRA1GABRB2HPGDTSHRSIRT2 | |
| SCHEMBL9752907 | 0.77 | ALDH1A1 (0.41) | MAOAMAOBNISCHTSHR | |
| SCHEMBL29629310 | 0.77 | NISCH (0.40) | MAOAMAOBNISCHGABRA1GABRB2 | |
| SCHEMBL10400814 | 0.75 | TSHR (0.43) | MAOAMAOBNISCHGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000009-A1 | NOVEL GLYOXYLATES AND HERBICIDAL AND PLANT GROWTH REGULANT ACTIVITY OF GLYOXYLATES | FERMENTA ASC CORPORATION (US) | 1991-01-10 | — | — | WO | disclosed |
| US-4976770-A | POSTEMERGENCE, PREEMERGENCE HERBICIDES | FERMENTA ASC CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |