SCHEMBL975316

SCHEMBL975316

Cc1ccc([Si](O[Cr](=O)(=O)O[Si](c2ccc(C)cc2C)(c2ccc(C)cc2C)c2ccc(C)cc2C)(c2ccc(C)cc2C)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
GAA P10253 2/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4660560 0.87 TP53 (0.38) TP53TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL1992127 0.70 TDP1 (0.42) TP53TDP1MEN1KMT2ANPSR1
SCHEMBL7028689 0.69 TRPA1 (0.34) TDP1SMN1; SMN2MAPTCYP1A2CYP2A6
SCHEMBL14359513 0.69 TDP1 (0.34) TP53TDP1ALDH1A1CYP1A2CYP2A6
SCHEMBL3109782 0.69 TDP1 (0.41) TP53TDP1SMN1; SMN2GAAALDH1A1
SCHEMBL28033237 0.68 TDP1 (0.44) TP53TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL1317920 0.66 TDP1 (0.42) TP53TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL1686578 0.66 TDP1 (0.48) TP53TDP1MEN1KMT2AGAA
SCHEMBL7778417 0.66 TDP1 (0.42) TP53TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL1686941 0.66 TDP1 (0.48) TP53TDP1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9303103-B2 Modified chromium-based catalysts and polymerization processes for using the same UNIVATION TECHNOLOGIES, LLC (US) 2016-04-05 US claimed
EP-2247630-B1 MODIFIED CHROMIUM-BASED CATALYSTS AND POLYMERIZATION PROCESSES FOR USING THE SAME UNIVATION TECH LLC (US) 2016-02-24 EP claimed
JP-2011513533-A 2011-04-28 JP claimed
EP-1697429-B1 BLOW MOLDING RESINS WITH IMPROVED ESCR UNION CARBIDE CHEM PLASTIC (US) 2011-01-26 EP claimed
US-20110010938-A1 Modified Chromium-Based Catalysts and Polymerization Processes for Using the Same UNIVATION TECHNOLOGIES, LLC (US) 2011-01-20 US claimed
EP-2247630-A1 MODIFIED CHROMIUM-BASED CATALYSTS AND POLYMERIZATION PROCESSES FOR USING THE SAME Univation Technologies, LLC (US) 2010-11-10 EP claimed
US-20090306317-A1 Process for the Preparation of a Silylchromate Catalyst SAUDI BASIC INDUSTRIES CORPORATION (SA) 2009-12-10 US claimed
WO-2009108174-A1 MODIFIED CHROMIUM-BASED CATALYSTS AND POLYMERIZATION PROCESSES FOR USING THE SAME UNIVATION TECHNOLOGIES, LLC (US) 2009-09-03 WO claimed
EP-1611171-B1 CHROMIUM-BASED CATALYSTS IN MINERAL OIL FOR PRODUCTION OF POLYETHYLENE UNION CARBIDE CHEM PLASTIC (US) 2009-07-01 EP claimed
EP-0626256-B1 Hollow multi-layer molding MITSUBISHI CHEM CORP (JP) 1997-08-06 EP claimed
US-5443874-A Laminate including high molecular weight polyethylene formed with reducing agent and silyl chromate catalyst, barrier layer of polyamide, saponified ethylene-vinyl acetate, thermoplastic polyester or blend, adhesive of acid-modified polyethylene MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-08-22 US claimed
EP-0626256-A1 Hollow multi-layer molding MITSUBISHI CHEMICAL CORPORATION (JP) 1994-11-30 EP claimed
EP-3802640-B1 UNIMODAL POLYETHYLENE COPOLYMER AND FILM THEREOF UNIVATION TECH LLC (US) 2025-10-22 EP disclosed
EP-3831479-B1 POLYOLEFIN PRODUCTION WITH CHROMIUM-BASED CATALYSTS UNIVATION TECH LLC (US) 2025-07-16 EP disclosed
US-12240927-B2 Unimodal polyethylene copolymer and film thereof UNIVATION TECHNOLOGIES, LLC (US) 2025-03-04 US disclosed
US-20250019475-A1 UNIMODAL POLYETHYLENE COPOLYMER AND FILM THEREOF UNIVATION TECHNOLOGIES, LLC 2025-01-16 US disclosed
US-5443874-A Laminate including high molecular weight polyethylene formed with reducing agent and silyl chromate catalyst, barrier layer of polyamide, saponified ethylene-vinyl acetate, thermoplastic polyester or blend, adhesive of acid-modified polyethylene MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-08-22 US disclosed
EP-0626256-A1 Hollow multi-layer molding MITSUBISHI CHEMICAL CORPORATION (JP) 1994-11-30 EP disclosed
US-5137994-A Forming hexene in situ, controlling density, copolymeriation; catalysts of complex of bis-trianlsilyl chromate and trihydrocarbylaluminum compound UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1992-08-11 US disclosed
US-4065612-A CHROMATE ON SILICA SUPPORT UNION CARBIDE CORPORATION (US) 1977-12-27 US disclosed