Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12679331 | 0.90 | — | — | |
| SCHEMBL22260762 | 0.73 | — | — | |
| Bicarbonate SCHEMBL1010325 | 0.67 | GSR (0.34) | — | |
| SCHEMBL13811273 | 0.65 | — | — | |
| SCHEMBL11106599 | 0.64 | SLC6A12 (0.32) | ABAT | |
| SCHEMBL11544608 | 0.64 | SLC6A12 (0.32) | ABAT | |
| SCHEMBL11544412 | 0.64 | SLC6A12 (0.32) | ABAT | |
| SCHEMBL6256551 | 0.64 | SLC6A12 (0.32) | ABAT | |
| SCHEMBL11279446 | 0.64 | SLC6A12 (0.41) | ABAT | |
| SCHEMBL7007768 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009589-A2 | MOUTH AND TOOTH CARE PREPARATIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-07-11 | — | — | WO | disclosed |