Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753351 | 0.90 | PTGS2 (0.32) | PTGS2KDM5B | |
| SCHEMBL9753644 | 0.88 | PTGS2 (0.36) | PTGS2KMT2AKDM5BALDH1A1POLB | |
| SCHEMBL9753426 | 0.83 | GCGR (0.40) | KDM5BALDH1A1MAPTCYP2C9HPGD | |
| SCHEMBL9752928 | 0.82 | MAPK14 (0.43) | PTGS2KMT2AKDM5BALDH1A1POLB | |
| SCHEMBL9753416 | 0.82 | POLB (0.37) | PTGS2KMT2AKDM5BALDH1A1POLB | |
| SCHEMBL9753119 | 0.81 | PTGS2 (0.36) | PTGS2KMT2AKDM5BALDH1A1POLB | |
| SCHEMBL9753114 | 0.81 | MAPK14 (0.42) | PTGS2KMT2AKDM5BALDH1A1POLB | |
| SCHEMBL9753104 | 0.79 | HMGCR (0.49) | PTGS2ALDH1A1CYP2C9 | |
| SCHEMBL9753217 | 0.79 | HMGCR (0.38) | ALDH1A1 | |
| SCHEMBL9753223 | 0.79 | HMGCR (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |