Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753358 | 1.00 | GABBR2 (0.34) | GABBR2GABBR1PTGS1PTGS2 | |
| SCHEMBL9753039 | 0.91 | PTGS1 (0.33) | PTGS1PTGS2 | |
| SCHEMBL9753395 | 0.83 | DHODH (0.36) | PTGS1PTGS2 | |
| SCHEMBL9753328 | 0.82 | PTGS1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL9753316 | 0.81 | KDM5B (0.32) | PTGS1PTGS2 | |
| SCHEMBL9753312 | 0.81 | KDM5B (0.32) | PTGS1PTGS2 | |
| SCHEMBL9753389 | 0.79 | KDM5B (0.32) | PTGS1PTGS2 | |
| SCHEMBL9753392 | 0.79 | KDM5B (0.32) | PTGS1PTGS2 | |
| SCHEMBL9752989 | 0.76 | KDM5B (0.34) | PTGS1PTGS2 | |
| SCHEMBL9753682 | 0.76 | MAPK14 (0.40) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |