Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.31 |
| ▸ | GCGR | P47871 | 3/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753395 | 0.85 | DHODH (0.36) | PTGS1PTGS2CSNK1DCSNK1E | |
| SCHEMBL9753039 | 0.85 | PTGS1 (0.33) | PTGS1PTGS2 | |
| SCHEMBL9753358 | 0.82 | GABBR2 (0.34) | PTGS1PTGS2 | |
| SCHEMBL9753366 | 0.82 | GABBR2 (0.34) | PTGS1PTGS2 | |
| SCHEMBL9753720 | 0.80 | GCGR (0.38) | TGFBR1GCGRTGFBR2CSNK1DCSNK1E | |
| SCHEMBL27529261 | 0.78 | PTGS1 (0.31) | PTGS1PTGS2 | |
| SCHEMBL9753406 | 0.78 | GCGR (0.38) | TGFBR1GCGRTGFBR2CSNK1DCSNK1E | |
| SCHEMBL9753309 | 0.75 | MAPK14 (0.43) | PTGS2TGFBR1GCGRTGFBR2 | |
| SCHEMBL9753771 | 0.75 | GCGR (0.40) | TGFBR1GCGRTGFBR2 | |
| SCHEMBL9752952 | 0.74 | GCGR (0.39) | PTGS1PTGS2TGFBR1GCGRTGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |