Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.36 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.34 |
| ▸ | GLRB | P48167 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 2/20 | 0.31 |
| ▸ | LDHB | P07195 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753039 | 0.86 | PTGS1 (0.33) | PTGS1PTGS2 | |
| SCHEMBL9753328 | 0.85 | PTGS1 (0.32) | PTGS1PTGS2CSNK1DCSNK1E | |
| SCHEMBL9753366 | 0.83 | GABBR2 (0.34) | PTGS1PTGS2 | |
| SCHEMBL9753358 | 0.83 | GABBR2 (0.34) | PTGS1PTGS2 | |
| SCHEMBL27349905 | 0.76 | PTGER1 (0.38) | DHODHPTGER1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL9753357 | 0.74 | PTGER1 (0.36) | DHODHPTGER1PTGS1PTGS2KDM4E | |
| SCHEMBL9753363 | 0.72 | DHODH (0.38) | DHODHPTGER1PTGS2KDM4EALDH1A1 | |
| SCHEMBL9752927 | 0.72 | PTGER1 (0.41) | DHODHPTGER1KDM4EALDH1A1 | |
| SCHEMBL9752984 | 0.68 | ALDH1A1 (0.41) | PTGS2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL27352605 | 0.67 | KDM4E (0.38) | DHODHPTGS2KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |