SCHEMBL9753374

SCHEMBL9753374

Cc1ccc2c(-c3ccc(F)cc3)c(CO)c(C(C)C)nn12

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 19/20 0.57
MAPK14 Q16539 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5089932 0.86 GCGR (0.53) GCGRMAPK14
SCHEMBL5089728 0.85 GCGR (0.58) GCGR
SCHEMBL9753342 0.81 GCGR (0.55) GCGR
SCHEMBL9752933 0.78 GCGR (0.54) GCGRMAPK14
SCHEMBL9752903 0.78 MAPK14 (0.43) GCGRMAPK14
SCHEMBL9753309 0.78 MAPK14 (0.43) GCGRMAPK14
SCHEMBL3820745 0.77 MAPT (0.47) GCGR
SCHEMBL9753368 0.77 GCGR (0.51) GCGR
SCHEMBL8949822 0.75 GCGR (0.88) GCGR
SCHEMBL9752948 0.74 MAPK14 (0.40) GCGRMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991018903-A1 PYRROLOPYRIDAZINE COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-12-12 WO disclosed