Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 6/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753207 | 0.86 | ALDH1A1 (0.40) | HMGCRALDH1A1GCGRPTGS2 | |
| SCHEMBL9753399 | 0.84 | FABP3 (0.41) | HMGCRMEN1CASP3BLMKMT2A | |
| SCHEMBL9752959 | 0.83 | POLB (0.38) | HMGCRMEN1KMT2AALDH1A1STAT1 | |
| SCHEMBL9753368 | 0.83 | GCGR (0.51) | GCGR | |
| SCHEMBL9753242 | 0.81 | HMGCR (0.57) | HMGCRPTGS2 | |
| SCHEMBL9753234 | 0.81 | HMGCR (0.47) | HMGCR | |
| SCHEMBL9753235 | 0.81 | HMGCR (0.47) | HMGCR | |
| SCHEMBL9753118 | 0.78 | HMGCR (0.67) | HMGCR | |
| SCHEMBL9753117 | 0.78 | HMGCR (0.67) | HMGCR | |
| SCHEMBL9752903 | 0.77 | MAPK14 (0.43) | HMGCRALDH1A1GCGRPTGS2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |